Case Study

TGen Secures Genome Data for Richer Healthcare AI Models with Fortanix Confidential Computing

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Customer Profile 

The Translational Genomics Research Institute (TGen) founded in 2002, is a non-profit genomics research institute based in Arizona, United States. TGen seeks to employ genetic discoveries to improve disease outcomes by developing smarter diagnostics and targeted therapeutics.

Industry

Medical Healthcare

Use Cases

Integrated Data Security Services

Products

Products

Confidential AI

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Challenge

The Problem of Securing Data Privacy within AI

  • TGen has several researchers working on different aspects of Cancer, Alzheimer’s, and other healthcare related research projects and they also have several clinicians involved in clinical trials. The primary challenge TGen faced while developing quality AI models in the past was the inadequacy of quality data. Having access to quality datasets is important for the progression of research. Even though they were accessing genome patterns from different sources, the lack of sufficient high-quality data was hampering their research initiatives. The requirement was both in terms of the adaptive breadth of the data as well as just how well it was curated.
  • And the primary impediment to accessing more datasets was the proliferation of data privacy regulations within healthcare. For example: In the USA, under the provisions of the Health Insurance Portability and Accountability Act 1996 (HIPAA), the HIPAA Security Rule defines the privacy requirements for all individually identifiable health information (e-PHI) that is created, received, maintained, or transmitted by a healthcare entity and stipulates protection against “anticipated impermissible uses or disclosures”.

Challenge

Solutions

Compliance

Sequential AI model chain and source genomic data is processed within the EU with auditable compliance of geo-fencing.

Encryption

End-to-end data encryption with critical application security and data provenance using Intel® SGX secure enclaves.

Ai

Intel® Xeon® E-3 (Ice Lake-SP) hardware with Intel® SGX and up to 1TB EPC deployed to provide acceleration of AI workloads.

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As of August 2025

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